Metabolic & longevity support
Metformin for longevity, prescribed online
Metformin is a decades-old metabolic medication being studied for healthy aging because of its effects on insulin sensitivity, inflammation and cellular pathways like AMPK. The large TAME trial is testing whether it slows aging itself. On FaroRx, provider-supervised metformin is $89 per quarter (a 180-tablet supply).
What is Metformin?
Metformin has been used for type 2 diabetes for over 60 years. Researchers became interested in it for longevity after observing that diabetics taking metformin sometimes outlived non-diabetic controls. It activates AMPK — a cellular energy sensor linked to many of the same pathways as exercise and caloric restriction.
Dosing
One daily tablet, typically started at a low dose (e.g. 500 mg) with food and increased as tolerated. Your provider sets the dose and monitors your response.
Who it's for
- Adults interested in evidence-informed longevity interventions
- Patients with insulin resistance or prediabetic markers
- Longevity patients building a stack alongside NAD+ or lifestyle changes
What's in the box
- Monthly metformin tablets
- Dosing instructions
- Provider follow-up check-ins
How Metformin works
Improves insulin sensitivity
Better glucose handling is one of the most reliable levers in metabolic health.
Activates AMPK
The same cellular energy-sensing pathway triggered by exercise and fasting.
Low-grade inflammation
Studies associate metformin with reduced markers of chronic inflammation ("inflammaging").
Side effects, honestly
Every medication has tradeoffs. Here's what to know before you start — your provider reviews your full history before prescribing.
- Mild stomach upset or loose stools when starting (usually passes)
- Reduced B12 absorption with long-term use — your provider may suggest monitoring
- Avoid with significant kidney or liver disease — your provider screens for this
How it works
Tell us your goal — weight, longevity, hair or strength — and a bit of health history. About three minutes.
A licensed U.S. provider reviews your intake and, if treatment is appropriate, builds a plan for your category.
Your medication and supplies arrive free and discreetly, with check-ins and dose adjustments along the way.
Metformin questions
Is metformin anti-aging?
It is one of the most studied candidates. Metformin affects pathways linked to aging (AMPK, insulin signaling, inflammation), and the TAME trial is testing directly whether it slows aging in humans. It is prescribed off-label for longevity — evidence is promising but not settled.
How do I get metformin for anti-aging?
Through a provider who prescribes it off-label. On FaroRx you complete an online intake, a licensed provider reviews your history and labs where relevant, and if appropriate it ships to you at $89 per quarter (a 180-tablet supply).
What dose of metformin is used for longevity?
Protocols commonly use 500-1,000 mg daily, lower than typical diabetes doses. Your provider individualizes it.
What are the side effects?
The most common is mild gastrointestinal upset when starting, which usually resolves with slow titration and taking it with food. Long-term use can lower B12 levels, so monitoring is sensible.
Can I take metformin with NAD+ or other longevity protocols?
They target different pathways and are often combined. Share your full regimen during your intake so your provider can confirm the combination is right for you.
Does metformin cause weight loss?
Modest weight loss (a few pounds) is common in the first months, mostly from appetite and glucose effects. It is not a primary weight loss drug — GLP-1s are far more effective for that goal.
Ready to start Metformin?
Complete a short online visit and a licensed provider will review whether it's right for you.
Compounded medications are prepared by a licensed U.S. pharmacy and are not FDA-approved products. Treatment is only prescribed if appropriate after a provider review.