Explainer
GHK-Cu cream: what it is and does it actually work?
Reviewed by the FaroRx clinical team · Updated September 2026
The short answer
GHK-Cu is a naturally occurring copper peptide that signals the skin to produce collagen and elastin and supports repair. Levels fall sharply with age. Applied topically it is one of the better-supported anti-ageing ingredients for firmness, fine lines and skin texture, with visible change usually appearing after six to twelve weeks of nightly use. FaroRx compounded GHK-Cu cream starts at $109 per month.
What GHK-Cu does to skin
- Signals fibroblasts to produce collagen and elastin.
- Supports wound healing and barrier repair.
- Improves firmness and fine lines over weeks, not days.
- Better tolerated than retinoids for sensitive or reactive skin.
How to use it
Apply nightly to clean, dry skin. Copper peptides and strong acids or high-strength vitamin C can destabilise each other, so use them at opposite ends of the day rather than layering. Give it a full twelve weeks before judging.
The FaroRx safety note
FaroRx medications are prescription-only. A licensed provider reviews your intake, medical history and medication list before anything is prescribed, and can decline if a treatment is not appropriate for you. Nothing here is medical advice.
Treatments mentioned
Common questions
How long does GHK-Cu take to work?
Most people see texture and firmness changes between six and twelve weeks of nightly use.
Can I use GHK-Cu with vitamin C?
Use them at different times of day — copper peptides and high-strength vitamin C can interfere with one another.
Is copper peptide safe for sensitive skin?
It is generally well tolerated and is often chosen by people who cannot use retinoids, but patch test first.
Get GHK-Cu cream
Complete a short online visit and a licensed provider will review whether treatment is right for you.
This guide is for information only and is not medical advice. Compounded medications are prepared by a licensed U.S. pharmacy and are not FDA-approved products.